Invention Grant
- Patent Title: Organ protection in PSMA-targeted radionuclide therapy of prostate cancer
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Application No.: US14846252Application Date: 2015-09-04
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Publication No.: US09956305B2Publication Date: 2018-05-01
- Inventor: John W. Babich , Shawn Hillier , John Joyal
- Applicant: Molecular Insight Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Molecular Insight Pharmaceuticals, Inc.
- Current Assignee: Molecular Insight Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Jeffrey R. Lomprey
- Main IPC: A61K51/04
- IPC: A61K51/04 ; A61K31/555 ; A61K51/12

Abstract:
A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a surface of the non-cancerous tissue, provided that the administration is carried out after a waiting period that follows administration of a compound including a radionuclide to the patient, the compound having affinity for both a cancerous tissue and the non-cancerous tissue, and, further provided that the binding sites have an affinity for both the agent and the compound.
Public/Granted literature
- US20160067361A1 ORGAN PROTECTION IN PSMA-TARGETED RADIONUCLIDE THERAPY OF PROSTATE CANCER Public/Granted day:2016-03-10
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