Provided is tissue paper which has softness, smoothness, and moistness either equaling or surpassing those of the existing moisturizing tissue paper and which is also less sticky and is not easily torn in use. The two-ply chemicals applied tissue paper has a configuration in which the amount of the chemicals applied on both side surfaces is 2.0 to 5.5 g/m2, the basis weight per each layer of sheets constituting the two-ply chemicals applied tissue paper is 10 to 25 mg/m2, and the thickness of the two-ply chemicals applied tissue paper is 100 to 140 μm.