Invention Grant
- Patent Title: Antimicrobial compounds
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Application No.: US15033686Application Date: 2014-10-29
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Publication No.: US09957226B2Publication Date: 2018-05-01
- Inventor: Roger Stromberg , Hakan Ottoson , Birgitta Agerberth , Gudmundur Gudmundsson , Erica Miraglia , Frank Nylen
- Applicant: AKTHELIA PHARMACEUTICALS
- Applicant Address: IS Reykjavik
- Assignee: Akthelia Pharmaceuticals
- Current Assignee: Akthelia Pharmaceuticals
- Current Assignee Address: IS Reykjavik
- Agency: Andrus Intellectual Property Law, LLP
- Priority: GB1319277.8 20131031
- International Application: PCT/IB2014/065678 WO 20141029
- International Announcement: WO2015/063694 WO 20150507
- Main IPC: A61K31/166
- IPC: A61K31/166 ; A61K31/167 ; C07C233/80 ; C07C235/56 ; C07C271/18 ; C07C271/22 ; C07D213/30 ; C07D249/04

Abstract:
The invention provides compounds for use in treating microbial infection in an animal. Example compounds include Pyridin-3-ylmethyl (4-((2-aminophenyl)-carbamoyl)benzyl)carbamate (“Entinostat”). The compounds can act via induction of the innate antimicrobial peptide defense system, and stimulation of autophagy.
Public/Granted literature
- US20160257642A1 ANTIMICROBIAL COMPOUNDS Public/Granted day:2016-09-08
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