Invention Grant
- Patent Title: Amido compounds and their use as pharmaceuticals
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Application No.: US15602693Application Date: 2017-05-23
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Publication No.: US09957229B2Publication Date: 2018-05-01
- Inventor: Wenqing Yao , Jincong Zhuo , Meizhong Xu , Colin Zhang , Brian W. Metcalf , Chunhong He , Ding-Quan Qian
- Applicant: Incyte Corporation , Incyte Holdings Corporation
- Applicant Address: US DE Wilmington US DE Wilmington
- Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee Address: US DE Wilmington US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D471/10
- IPC: C07D471/10 ; C07D207/06 ; A61K31/407 ; C07D491/107 ; C07D513/10 ; C07D498/20 ; C07D495/04 ; C07D493/10 ; C07D491/20 ; C07D491/10 ; C07D487/10 ; C07D487/08 ; C07D487/04 ; C07D471/04 ; C07D417/04 ; C07D413/14 ; C07D413/10 ; C07D405/14 ; C07D405/04 ; C07D403/04 ; C07D401/14 ; C07D401/10 ; C07D401/06 ; C07D401/04 ; C07D333/34 ; C07D295/185 ; C07D221/20 ; C07D217/26 ; C07D217/06 ; C07D213/38 ; C07D211/70 ; C07D211/66 ; C07D211/64 ; C07D211/58 ; C07D211/52 ; C07D211/48 ; C07D211/46 ; C07D211/34 ; C07D211/22 ; C07D211/18 ; C07D211/16 ; C07D209/70 ; C07D209/62 ; C07D209/52 ; C07D209/44 ; C07D209/42 ; C07D209/08 ; C07D207/27 ; C07D207/16 ; C07D207/14 ; C07D207/12 ; C07D207/10 ; C07D207/08 ; A61K31/4439
Abstract:
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Public/Granted literature
- US20170334847A1 Amido Compounds And Their Use As Pharmaceuticals Public/Granted day:2017-11-23
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