Invention Grant
- Patent Title: Iodine(II)-mediated radiofluorination
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Application No.: US15231470Application Date: 2016-08-08
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Publication No.: US09957231B2Publication Date: 2018-05-01
- Inventor: Neil Vasdev , Benjamin H. Rotstein , Nickeisha A. Stephenson , Huan Liang
- Applicant: The General Hospital Corporation
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: C07D213/57
- IPC: C07D213/57 ; C07D239/553 ; C07D319/06 ; C07D319/08 ; C07D405/12 ; C07J17/00 ; C07J1/00 ; C07J51/00 ; C07B59/00
Abstract:
A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using 18F is described. Processes, intermediates, reagents and radiolabelled compounds are described.
Public/Granted literature
- US20160362375A1 Iodine(III)-Mediated Radiofluorination Public/Granted day:2016-12-15
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