Invention Grant
- Patent Title: Anti-FLT-1 antibodies in treating duchenne muscular dystrophy
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Application No.: US14763881Application Date: 2014-01-28
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Publication No.: US09957324B2Publication Date: 2018-05-01
- Inventor: Serene Josiah , Thomas M. Luby , Atsushi Asakura , Dennis Keefe , Lawrence Charnas , Mayank Verma
- Applicant: SHIRE HUMAN GENETIC THERAPIES, INC. , REGENTS OF THE UNIVERSITY OF MINNESOTA
- Applicant Address: US MA Lexington US MN Minneapolis
- Assignee: Shire Human Genetic Therapies, Inc.,Regents of the University of Minnesota
- Current Assignee: Shire Human Genetic Therapies, Inc.,Regents of the University of Minnesota
- Current Assignee Address: US MA Lexington US MN Minneapolis
- Agency: Proskauer Rose LLP
- Agent Fangli Chen; Julio J. Mendez
- International Application: PCT/US2014/013402 WO 20140128
- International Announcement: WO2014/117160 WO 20140731
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00

Abstract:
The present invention provides, among other things, methods and compositions for treating muscular dystrophy, in particular, Duchenne muscular dystrophy (DMD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to DMD an effective amount of an anti-Flt-1 antibody, or antigen binding fragment thereof, such that at least one symptom or feature of DMD is reduced in intensity, severity, or frequency, or has delayed onset.
Public/Granted literature
- US20150361174A1 ANTI-FLT-1 ANTIBODIES IN TREATING DUCHENNE MUSCULAR DYSTROPHY Public/Granted day:2015-12-17
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