Invention Grant
- Patent Title: Treatment of LCAT gene related diseases by inhibition of a natural antisense transcript to LCAT
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Application No.: US14815007Application Date: 2015-07-31
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Publication No.: US09957503B2Publication Date: 2018-05-01
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7115 ; A61K31/712 ; A61K31/713 ; A61K48/00

Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Lipid transport and metabolism gene, in particular, by targeting natural antisense polynucleotide of a Lipid transport and metabolism gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of a Lipid transport and metabolism genes.
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