Invention Grant
- Patent Title: Functionalization of endogenous bacteria
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Application No.: US14320965Application Date: 2014-07-01
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Publication No.: US09957511B2Publication Date: 2018-05-01
- Inventor: Timothy Kuan-Ta Lu , Robert James Citorik , James Collins , Russell-John Krom
- Applicant: Massachusetts Institute of Technology , Trustees of Boston University
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: Massachusetts Institute of Technology,Trustees of Boston University
- Current Assignee: Massachusetts Institute of Technology,Trustees of Boston University
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12N15/74 ; C12N15/70
Abstract:
Various aspects and embodiments of the present disclosure are directed to methods and compositions for functionalizing endogenous bacteria in vivo. The methods include delivering to endogenous bacterial cells a recombinant bacteriophage or phagemid that is engineered to contain at least one genetic circuit.
Public/Granted literature
- US20150004705A1 FUNCTIONALIZATION OF ENDOGENOUS BACTERIA Public/Granted day:2015-01-01
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