A system for localization of a radio frequency source in a region includes a first plurality of antennas disposed about the region, a second plurality of antennas disposed about the region, a first radio frequency positioning module in communication with the first plurality of antennas and configured to determine a plurality of spatially separated candidate locations in the region for the radio frequency source, a second radio frequency positioning module in communication with the second plurality of antennas and configured to determine a sub-region of the region, the sub-region including the radio frequency source, and a resolution module for identifying a subset of the candidate locations in the sub-region of the region.