The present disclosure provides a method and a system for fall detection. Measurement signals are received from a plurality of sensors to monitor user activities, the plurality of sensors including a motion sensor for collecting motion information and a biomedical sensor for collecting physiological information. According to a signal processing sequence, whether the measurement signals meet multiple qualifying conditions for a fall incident is determined. The multiple qualifying conditions include: a condition evaluating at least the motion information, and a condition evaluating at least the physiological information. The method further includes: when the measurement signals do not meet the multiple qualifying conditions, continuing to monitor the user activities; and when the measurement signals meet the multiple conditions, determining that a fall incident has occurred, and sending an alert message to a designated contact.