Invention Grant
- Patent Title: Halogenated esters of cyclopropanated unsaturated fatty acids for use in the treatment of neurodegenerative diseases
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Application No.: US15028487Application Date: 2014-10-20
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Publication No.: US09962357B2Publication Date: 2018-05-08
- Inventor: Thomas J. Nelson , Daniel L. Alkon
- Applicant: Blanchette Rockefeller Neurosciences Institute
- Applicant Address: US WV Morgantown
- Assignee: West Virginia University
- Current Assignee: West Virginia University
- Current Assignee Address: US WV Morgantown
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/US2014/061368 WO 20141020
- International Announcement: WO2015/058191 WO 20150423
- Main IPC: A01N43/20
- IPC: A01N43/20 ; A01N43/24 ; A61K31/335 ; A61K31/23 ; C07C69/635 ; A61K31/202 ; A61K31/336
Abstract:
The present disclosure describes novel PKC-ϵ activators chosen from halogenated esters of unsaturated fatty acids derivatives thereof, including halogenated esters of both polyunsaturated and monunsaturated fatty acids and derivatives thereof. The disclosure further relates to compositions, kits, and methods for treatment using the halogenated esters.
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