Invention Grant
- Patent Title: Methyl-piperidine compounds useful for inhibiting microsomal prostaglandin E2 synthase-1
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Application No.: US15520462Application Date: 2015-10-22
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Publication No.: US09962375B2Publication Date: 2018-05-08
- Inventor: Matthew Joseph Fisher , Steven Lee Kuklish , Peter Rudolph Manninen , Katherine Marie Partridge , Matthew Allen Schiffler , Alan M. Warshawsky , Jeremy Schulenburg York
- Applicant: Eli Lilly and Company
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Dan I. Wood; James B. Myers
- International Application: PCT/US2015/056960 WO 20151022
- International Announcement: WO2016/069376 WO 20160506
- Main IPC: A61K31/451
- IPC: A61K31/451 ; A61K31/4709 ; A61K31/506 ; C07D401/04 ; C07D405/14 ; C07D211/62 ; A61K31/00 ; C07D211/00
Abstract:
The present invention provides compounds of Formula (1), or a pharmaceutically acceptable salt thereof, formula (1), where R, R1, and G are as described herein; methods of preparing the compounds; and use of the compounds to treat pain and/or inflammation associated with arthritis or osteoarthritis.
Public/Granted literature
- US20170326128A1 Novel Methyl-Piperidine Compounds Useful for Inhibiting Microsomal Prostaglandin E2 Synthase-1 Public/Granted day:2017-11-16
Information query
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