Invention Grant
- Patent Title: Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use
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Application No.: US15209594Application Date: 2016-07-13
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Publication No.: US09962379B2Publication Date: 2018-05-08
- Inventor: Jonathan Jacob Sabbagh , Chad Dickey
- Applicant: Jonathan Jacob Sabbagh , Chad Dickey
- Applicant Address: US FL Tampa US DC Washington
- Assignee: UNIVERSITY OF SOUTH FLORIDA,THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Current Assignee: UNIVERSITY OF SOUTH FLORIDA,THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Current Assignee Address: US FL Tampa US DC Washington
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K31/5415 ; A61K31/4168 ; A61K31/454 ; A61K31/138 ; A61K31/36 ; A61K31/137 ; A61K31/135 ; A61K31/15 ; A61K31/42 ; A61K31/46 ; A61K45/06 ; C12Q1/533
Abstract:
The subject invention concerns materials and methods for treating depression, stress disorders, such as PTSD, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit FKBP51 activity or function. The subject invention also concerns a method for inhibiting activity of the FKBP51 protein in a cell. The subject invention also concerns methods of screening for compounds or drugs that inhibit the FKBP51 protein.
Public/Granted literature
- US20170000785A1 INHIBITORS OF THE FKBP51 PROTEIN FROM A HIGH-THROUGHPUT DRUG SCREEN AND METHODS OF USE Public/Granted day:2017-01-05
Information query
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