Invention Grant
- Patent Title: Sulfonamide compounds for inhibition of metastatic tumor growth
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Application No.: US15270742Application Date: 2016-09-20
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Publication No.: US09962398B2Publication Date: 2018-05-08
- Inventor: Claudiu Supuran , Shoukat Dedhar , Paul C. McDonald , Fabrizio Carta
- Applicant: Welichem Biotech Inc.
- Applicant Address: CA Burnaby
- Assignee: Welichem Biotech Inc.
- Current Assignee: Welichem Biotech Inc.
- Current Assignee Address: CA Burnaby
- Agency: Oyen Wiggs Green & Mutala LLP
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/63 ; A61K45/06 ; C07C311/47 ; A61K31/277
Abstract:
Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar—SO2NH2 are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals.
Public/Granted literature
- US20170007627A1 NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH Public/Granted day:2017-01-12
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