Invention Grant
- Patent Title: Compositions comprising cocktails of antibacterial phages and uses thereof for the treatment of bacterial infections
-
Application No.: US14385828Application Date: 2013-03-19
-
Publication No.: US09962419B2Publication Date: 2018-05-08
- Inventor: João João Duarte Alves Mendes , Clara Isabel Rodrigues Leandro , Sofia Volker Côrte-Real
- Applicant: TECNIFAR—INDUSTRIA TECNICA FARMACEUTICA, S.A. , TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA
- Applicant Address: PT Lisboa
- Assignee: Tecnifar—Industria Tecnica Farmaceutica, S.A. Technophage, Investigação E Desenvolvimento Em Biotecnologia, SA
- Current Assignee: Tecnifar—Industria Tecnica Farmaceutica, S.A. Technophage, Investigação E Desenvolvimento Em Biotecnologia, SA
- Current Assignee Address: PT Lisboa
- Agency: King & Spalding LLP
- Agent Margaret B. Brivanlou; Nicole Fortune
- International Application: PCT/PT2013/000016 WO 20130319
- International Announcement: WO2013/141730 WO 20130926
- Main IPC: A61K35/76
- IPC: A61K35/76 ; A61K45/06 ; C12N7/00 ; C12N9/50 ; A61B17/3205 ; A61K9/00 ; A61M1/00 ; A61K38/18 ; A61B17/32

Abstract:
The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections, in particular diabetic foot infections. More specifically, the present invention is directed to novel cocktails of bacteriophage strains F44/10, F1 25/10, F770/05, F510/08, F1 245/05, and/or variants thereof; and methods of using same in the treatment and prevention of bacterial infections, including cutaneous ulcers associated with diabetic foot infections, caused by, e.g., Staphylococcus aureus, Pseudomonas aeruginosa, and/or Acinetobacter baumannii. The cocktails are used as pharmaceutical compositions either alone or in further combination with other therapies, e.g., antibiotics, growth factors, or other standard, as well as non-standard, therapies for diabetic foot infections.
Public/Granted literature
Information query