- Patent Title: Method for preparing an immunogenic lysate, the lysate obtained, dendritic cells loaded with such lysate and a pharmaceutical composition comprising the lysate or the dendritic cells
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Application No.: US14758153Application Date: 2013-12-20
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Publication No.: US09962433B2Publication Date: 2018-05-08
- Inventor: Josephus Petrus Johannes Jacobus Hegmans , Joan Geertrudis Jacobus Victor Aerts
- Applicant: Amphera B.V.
- Applicant Address: NL 's-Hertogenbosch
- Assignee: Amphera B.V.
- Current Assignee: Amphera B.V.
- Current Assignee Address: NL 's-Hertogenbosch
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Sunit Talapatra
- Priority: NL2010067 20121228
- International Application: PCT/EP2013/077837 WO 20131220
- International Announcement: WO2014/102220 WO 20140703
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N5/0784

Abstract:
The present invention relates to a method for the preparation of an immunogenic lysate from mesothelioma tumor cells, to such a lysate and to dendritic cells loaded with the lysate, the present invention further relates a pharmaceutical composition comprising such lysate or dendritic cells, to the use of the lysate, and to said loaded dendritic cells or said pharmaceutical composition for use in the prevention or treatment of mesothelioma.
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