Invention Grant
- Patent Title: Soluble complexes of drug analogs and albumin
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Application No.: US14765773Application Date: 2014-01-31
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Publication No.: US09962452B2Publication Date: 2018-05-08
- Inventor: Qun Sun
- Applicant: Zhuhai Beihai Biotech Co., Ltd.
- Applicant Address: CN Zhuhai
- Assignee: Zhuhai Beihai Biotech Co., Ltd.
- Current Assignee: Zhuhai Beihai Biotech Co., Ltd.
- Current Assignee Address: CN Zhuhai
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2014/014079 WO 20140131
- International Announcement: WO2014/121033 WO 20140807
- Main IPC: A61K31/337
- IPC: A61K31/337 ; A61K47/48 ; A61K31/4745
Abstract:
The present invention provides novel, non-covalently bound complexes of serum albumin and analogs of poorly soluble drugs, such as camptothecin. The novel complexes are significantly more water-soluble than the camptothecin analogs and are useful as prodrug forms of the camptothecin analogs for the treatment of mammalian cell proliferative diseases, such as cancer.
Public/Granted literature
- US20150366984A1 SOLUBLE COMPLEXES OF DRUG ANALOGS AND ALBUMIN Public/Granted day:2015-12-24
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