Invention Grant
- Patent Title: Anticancer drugs including the chemical structures of an androgen receptor ligand and a histone deacetylase inhibitor
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Application No.: US15417860Application Date: 2017-01-27
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Publication No.: US09963433B2Publication Date: 2018-05-08
- Inventor: Zhihui Qin
- Applicant: Wayne State University
- Applicant Address: US MI Detroit
- Assignee: Wayne State University
- Current Assignee: Wayne State University
- Current Assignee Address: US MI Detroit
- Agency: Lee & Hayes PLLC
- Agent C. Rachal Winger
- Main IPC: C07D233/86
- IPC: C07D233/86 ; A61K31/4178 ; A61K31/4166 ; C07F9/6506 ; C07D401/12
Abstract:
A novel class of drugs for treating androgen receptor (AR) positive cancer including prostate cancer and breast cancer are described. The drugs include the chemical scaffolds of a high affinity androgen receptor ligand and a histone deacetylase inhibitor. Also described are compositions including the novel drugs and methods of treating AR positive cancer using the compositions.
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