Invention Grant
- Patent Title: N-arylmethyl sulfonamide negative modulators of NR2A
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Application No.: US15024870Application Date: 2014-09-26
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Publication No.: US09963434B2Publication Date: 2018-05-08
- Inventor: David R Anderson , Robert A Volkmann
- Applicant: LUC THERAPEUTICS
- Applicant Address: US MA Cambridge
- Assignee: Luc Therapeutics, Inc.
- Current Assignee: Luc Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ziegler IP Law Group, LLC
- International Application: PCT/US2014/057795 WO 20140926
- International Announcement: WO2015/048503 WO 20150402
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D241/24 ; C07D401/12 ; C07D403/12 ; C07D417/12 ; C07D213/81 ; C07D213/82 ; C07D237/24 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/14

Abstract:
Compounds of the Formula wherein A, B, C, D, X, Y, Z, R1, R2, R2′, R3 and n are described herein, selectively negatively modulate NMDA receptors containing an NR2A subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.
Public/Granted literature
- US20160311782A1 N-ARYLMETHYL SULFONAMIDE NEGATIVE MODULATORS OF NR2A Public/Granted day:2016-10-27
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