Invention Grant
- Patent Title: Morphinan derivative
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Application No.: US15463418Application Date: 2017-03-20
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Publication No.: US09963460B1Publication Date: 2018-05-08
- Inventor: Hiroshi Nagase , Naoshi Yamamoto
- Applicant: University of Tsukuba , Nippon Chemiphar Co., Ltd.
- Applicant Address: JP Ibaraki JP Tokyo
- Assignee: University of Tsukuba,Nippon Chemiphar Co., Ltd.
- Current Assignee: University of Tsukuba,Nippon Chemiphar Co., Ltd.
- Current Assignee Address: JP Ibaraki JP Tokyo
- Agency: Wood Herron & Evans LLP
- Priority: JP2017-023444 20170210
- Main IPC: C07D491/02
- IPC: C07D491/02 ; A61K31/445 ; C07D489/02

Abstract:
A morphinan derivative represented by the following formula (I), a tautomer or a stereoisomer of the compound, or a pharmaceutically acceptable salt thereof, or a solvate thereof, and a medicament, an analgesic and an antipruritic drug including the same as an active ingredient: wherein R is selected from hydrogen and C1-6 alkyl, and n represents an integer of 0 to 2.
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