Invention Grant
- Patent Title: Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds
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Application No.: US15034244Application Date: 2014-10-29
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Publication No.: US09963472B2Publication Date: 2018-05-08
- Inventor: Branko Jenko , Gregor Kosec , Hrvoje Petkovic , Ajda Podgorsek Berke , Jerca Pahor , Alen Cusak , Oda Cornelia Maria Sibon , Balaji Srinivasan
- Applicant: ACIES BIO D.O.O. , RIJKSUNIVERSITEIT GRONINGEN , ACADEMISCH ZIEKENHUIS GRONINGEN
- Applicant Address: SI Ljubljana NL Groningen NL Groningen
- Assignee: ACIES BIO D.O.O.,RIJKSUNIVERSITEIT GRONINGEN,ACADEMISCH ZIEKENHUIS GRONINGEN
- Current Assignee: ACIES BIO D.O.O.,RIJKSUNIVERSITEIT GRONINGEN,ACADEMISCH ZIEKENHUIS GRONINGEN
- Current Assignee Address: SI Ljubljana NL Groningen NL Groningen
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Xixi Sun
- Priority: EP13191457 20131104
- International Application: PCT/EP2014/073258 WO 20141029
- International Announcement: WO2015/063177 WO 20150507
- Main IPC: C07F9/09
- IPC: C07F9/09

Abstract:
The invention relates to (S)-acyl-4′-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.
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