Invention Grant
- Patent Title: Antioxidant compound having anti atherosclerotic effect and preparation thereof
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Application No.: US15443538Application Date: 2017-02-27
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Publication No.: US09963476B2Publication Date: 2018-05-08
- Inventor: Kotamraju Srigiridhar , Karnewar Santosh , Vasamsetti Sathish Babu , Togapur Pavan Kumar , Basi Venkata Subba Reddy , Jerald Mahesh Kumar
- Applicant: Council of Scientific and Industrial Research
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific and Industrial Research
- Current Assignee: Council of Scientific and Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Schwegman Lundberg & Woessner, P.A.
- Priority: IN478/DEL/2015 20150219
- Main IPC: C07F9/655
- IPC: C07F9/655
Abstract:
The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE−/− mice along with the endothelial cell age-delaying effects of Mito-Esc.
Public/Granted literature
- US20170240577A1 ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF Public/Granted day:2017-08-24
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