Invention Grant
- Patent Title: Methods of using compositions comprising variants and fusions of FGF19 polypeptides for reducing glucose levels in a subject
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Application No.: US14647627Application Date: 2013-11-26
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Publication No.: US09963494B2Publication Date: 2018-05-08
- Inventor: Lei Ling , Darrin Anthony Lindhout
- Applicant: NGM Biopharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: NGM Biopharmaceuticals, Inc.
- Current Assignee: NGM Biopharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Jones Day
- International Application: PCT/US2013/071803 WO 20131126
- International Announcement: WO2014/085365 WO 20140605
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/50 ; A61K45/06 ; G01N33/66
Abstract:
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and variants or fusions of FGF19 and/or FGF21 proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
Public/Granted literature
- US20150291677A1 COMPOSITIONS AND METHODS FOR TREATMENT OF METABOLIC DISORDERS AND DISEASES Public/Granted day:2015-10-15
Information query
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