Invention Grant
- Patent Title: LCMV-GP-VSV-pseudotyped vectors and tumor-infiltrating virus-producing cells for the therapy of tumors
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Application No.: US15482430Application Date: 2017-04-07
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Publication No.: US09963718B2Publication Date: 2018-05-08
- Inventor: Dorothee Von Laer , Tsanan Heimann
- Applicant: VIRATHERAPEUTICS GMBH
- Applicant Address: AT Innsbruck
- Assignee: VIRATHERAPEUTICS GMBH
- Current Assignee: VIRATHERAPEUTICS GMBH
- Current Assignee Address: AT Innsbruck
- Agency: Faegre Baker Daniels LLP
- Priority: DE102008050860 20081008
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C07K14/005 ; A61K48/00 ; C07K14/54 ; C07K14/52 ; C12N9/12
Abstract:
The invention relates to recombinant VSV viruses and viral vectors which produce a glycoprotein GP of the lymphocyte choriomeningitis virus (LCMV) instead of the G protein of the VSV, to virus producing cells which produce LCMV-GP-pseudotyped VSV virions, and to the use of said vectors and cells in the therapy of solid tumors, especially brain tumors.
Public/Granted literature
- US20170211096A1 LCMV-GP-VSV-Pseudotyped Vectors and Tumor-Infiltrating Virus-Producing Cells for the Therapy of Tumors Public/Granted day:2017-07-27
Information query
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