Invention Grant
- Patent Title: Strain secreting fatty acids by phospholipase and method for producing fatty acids using it
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Application No.: US14730174Application Date: 2015-06-03
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Publication No.: US09963722B2Publication Date: 2018-05-08
- Inventor: Jeong Kug Lee , Eui Jin Kim , Xiaomeng Tong , Eun Kyung Oh
- Applicant: SOGANG UNIVERSITY RESEARCH FOUNDATION
- Applicant Address: KR Seoul
- Assignee: SOGANG UNIVERSITY RESEARCH FOUNDATION
- Current Assignee: SOGANG UNIVERSITY RESEARCH FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: The PL Law Group, PLLC
- Priority: KR10-2014-0067747 20140603
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P7/64 ; C12N9/20 ; C12N9/10 ; C12N9/00 ; C12N9/18

Abstract:
A bacterial strain secreting fatty acids, the strain inducing fatty acids to be extracellularly secreted by using phospholipase expressed in the periplasmic space of cell. When a method of producing fatty acids by using the bacterial strain secreting fatty acids is used, fatty acids extracellularly secreted are continuously obtained without apoptosis, leading to lower costs and higher production efficiency. Phospholipase, unlike thioesterase, which is a typical fatty-acid degrading enzyme, decomposes phospholipid to produce free fatty acids. Accordingly, by using the substrate specificity of two different phospholipases, a fatty acid having a specific composition can be selectively produced. Unlike in a typical method in which fat is obtained from cells or tissues, fatty acids secreted during cell growth are obtainable by biding to a hydrophobic material without an extraction process using an organic solvent in large quantities. Accordingly, a more economical, environmentally friendly bio-oil production process can be realized.
Public/Granted literature
- US20160046968A1 Novel strain secreting fatty acids by phospholipase and method for producing fatty acids using it Public/Granted day:2016-02-18
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