Embodiments include computing devices, apparatus, and methods implemented by the apparatus for implementing profile guided indirect jump checking on a computing device, including encountering an indirect jump location of implementing an indirect jump during execution of a program, identifying an indirect jump target of the indirect jump, determining whether the indirect jump location and the indirect jump target are associated in a profile guided indirect jump table, and determining whether the indirect jump location and the indirect jump target are associated in a compiler guided indirect jump table in response to determining that the indirect jump location and the indirect jump target are not associated in the profile guided indirect jump table.