A hand hygiene compliance monitoring system includes a method and computer program product for performing sanitation compliance monitoring including receiving sanitation compliance data. The sanitation compliance data includes a zone identifier corresponding to a first device in a zone and an entity identifier corresponding to a second device attached to a mobile entity in the zone. The zone is defined by an area over which the first device and the second device communicate via one-way or two-way communication. It is determined whether the entity is compliant with a sanitation protocol associated with the zone, and a database is updated with results of the determining.