A power conversion topology and control method intended for use with a DC bus is disclosed, providing a means to prevent the flow of ground fault current while detecting a fault condition and optionally continuing to operate the DC bus. In one control configuration, a DC-DC power stage with an active current control loop drives differential current to zero, and a separate voltage control loop maintains the desired differential bus voltage. Absolute bus voltage with respect to ground is monitored in order to detect fault conditions. In another configuration, the absolute voltage of the bus with respect to ground is controlled and differential bus current is monitored to detect ground fault conditions.