Systems and processes of locating a medical imaging device relative to a person support apparatus and/or a patient are provided. An example system includes an optical sensor disposed at the person support apparatus and/or the imaging device. In embodiments, optical markers may also be disposed on one or more of the medical imaging device, the person support apparatus and/or patient for determining the relative location of the imaging device and the person support apparatus and/or patient. In other embodiments, an optical sensor may use image recognition processes to determine the relative locations. By locating and positioning the medical imaging device without taking recursive medical images to position the device, the imaging device can be positioned for a subsequent image without exposing the patient and healthcare professionals to additional radiation generated while positioning the medical imaging device, thereby reducing risk to the patient and the medical staff.