Invention Grant
- Patent Title: Staphylococcal coagulase antigens and methods of their use
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Application No.: US14397031Application Date: 2013-03-14
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Publication No.: US09968668B2Publication Date: 2018-05-15
- Inventor: Molly McAdow , Andrea Dedent , Alice Cheng , Carla Emolo , Dominique Missiakas , Olaf Schneewind
- Applicant: UNIVERSITY OF CHICAGO
- Applicant Address: US IL Chicago
- Assignee: The University of Chicago
- Current Assignee: The University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/US2013/031695 WO 20130314
- International Announcement: WO2013/162746 WO 20131031
- Main IPC: A61K39/08
- IPC: A61K39/08 ; C07K14/31 ; A61K39/085 ; C12N9/52 ; A61K38/48 ; A61K45/06 ; C07K16/12
Abstract:
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve coagulase Domains 1-2 and variants thereof.
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