Invention Grant
- Patent Title: Metabotropic glutamate receptor negative allosteric modulators (NAMS) and uses thereof
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Application No.: US15315363Application Date: 2015-06-09
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Publication No.: US09969726B2Publication Date: 2018-05-15
- Inventor: Nicholas David Peter Cosford , Dhanya Raveendra-Panickar , Douglas J. Sheffler
- Applicant: Sanford-Burnham Medical Research Institute
- Applicant Address: US CA La Jolla
- Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- Current Assignee Address: US CA La Jolla
- Agency: Wilson & Sonsini, Goodrich & Rosati
- International Application: PCT/US2015/034964 WO 20150609
- International Announcement: WO2015/191630 WO 20151217
- Main IPC: C07D239/26
- IPC: C07D239/26 ; C07D409/02 ; A61K31/506 ; A61K31/505 ; C07D417/14 ; C07D277/30 ; C07D277/26 ; C07D417/04 ; C07D417/10 ; C07D285/08 ; C07D275/02 ; C07D333/24 ; C07D307/38 ; C07D263/32 ; C07D271/06 ; C07D261/08 ; C07D249/08 ; C07D409/04 ; C07D401/04 ; C07D405/04 ; C07D405/10 ; C07D233/64 ; C07D231/12 ; C07D409/14 ; C07D413/04 ; C07D401/14 ; C07D413/14 ; C07D403/12 ; C07D401/10 ; C07D243/12

Abstract:
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
Public/Granted literature
- US20170217951A1 Metabotropic Glutamate Receptor Negative Allosteric Modulators (NAMS) and Uses Thereof Public/Granted day:2017-08-03
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