Invention Grant
- Patent Title: Pyrazolotriazines as inhibitors of nucleases
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Application No.: US15316764Application Date: 2015-06-17
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Publication No.: US09969741B2Publication Date: 2018-05-15
- Inventor: Jiri Damborsky , Fedor Nikulenkov , Alexandra Sisakova , Stepan Havel , Lumir Krejci , Benoit Carbain , Jan Brezovsky , Lukas Daniel , Kamil Paruch
- Applicant: MASARYKOVA UNIVERZITA
- Applicant Address: CZ Brno
- Assignee: MASARYKOVA UNIVERZITA
- Current Assignee: MASARYKOVA UNIVERZITA
- Current Assignee Address: CZ Brno
- Agency: Notaro, Michalos & Zaccaria P.C.
- Priority: EP14173242 20140620
- International Application: PCT/CZ2015/000063 WO 20150617
- International Announcement: WO2015/192817 WO 20151223
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53 ; A61P35/00
Abstract:
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Public/Granted literature
- US20170197966A1 PYRAZOLOTRIAZINES AS INHIBITORS OF NUCLEASES Public/Granted day:2017-07-13
Information query
