Invention Grant
- Patent Title: Methods of treating damaged cartilage tissue using growth factors fused to heparin binding sequences
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Application No.: US14877474Application Date: 2015-10-07
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Publication No.: US09969788B2Publication Date: 2018-05-15
- Inventor: Richard Lee
- Applicant: The Brigham and Women's Hospital, Inc.
- Applicant Address: US MA Boston
- Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee: The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- Main IPC: A61K38/30
- IPC: A61K38/30 ; C07K14/65 ; C07H21/04 ; C07K14/475 ; C07K14/49 ; C12N15/62 ; A61K35/30 ; A61K35/32 ; A61K35/34 ; C07K14/47 ; C12N5/0793 ; C12N5/077 ; A61K38/00
Abstract:
The present invention is directed to proteins in which a heparin binding peptide is fused to a growth factor that promotes cell growth and survival. The compound thus formed is bound to the surface of cells which are then administered to damaged tissue. The growth factor is thereby maintained at the site of administration where it promotes repair.
Public/Granted literature
- US20160024170A1 METHODS OF PROMOTING CARDIAC REPAIR USING GROWTH FACTORS FUSED TO HEPARIN BINDING SEQUENCES Public/Granted day:2016-01-28
Information query
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