Invention Grant
- Patent Title: Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1
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Application No.: US15427833Application Date: 2017-02-08
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Publication No.: US09970008B2Publication Date: 2018-05-15
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: CuRNA, Inc.
- Applicant Address: US FL Miami
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Current Assignee Address: US FL Miami
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/7125 ; A61K31/713 ; C07K2/00
Abstract:
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Atonal homolog 1 (ATOH1), in particular, by targeting natural antisense polynucleotides of Atonal homolog 1 (ATOH1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of ATOH1.
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