Invention Grant
- Patent Title: Methods for increasing CAS9-mediated engineering efficiency
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Application No.: US14836753Application Date: 2015-08-26
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Publication No.: US09970030B2Publication Date: 2018-05-15
- Inventor: Peter Sean Cameron , Rachel E. Haurwitz , Andrew P. May , Christopher H. Nye , Megan van Overbeek
- Applicant: Caribou Biosciences, Inc.
- Applicant Address: US CA Berkeley
- Assignee: Caribou Biosciences, Inc.
- Current Assignee: Caribou Biosciences, Inc.
- Current Assignee Address: US CA Berkeley
- Agent Gary R. Fabian; Barbara G. McClung
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N9/22 ; C07H21/04 ; C12N15/90 ; C12N15/11 ; C12N15/10 ; A01K67/00
Abstract:
Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
Public/Granted literature
- US20160257973A1 METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY Public/Granted day:2016-09-08
Information query
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