Systems and methods for optimizing signaling in a mobile network and conserving battery resources based on transport protocol layer such as Transmission Control Protocol (TCP) layer optimization techniques are disclosed. A distributed proxy system, in various embodiments, can implement one or more optimization techniques including deferring TCP socket closures or closing network sockets with TCP RST instead of TCP FIN to save on signaling in the wireless (e.g., mobile network) and conserve battery resources. In some embodiments, the disclosed system can implement various methods to prevent or reduce number of TCP and/or application level retries, and thereby reduce signaling in the wireless network and conserve battery resources. In other embodiments, the distributed proxy system can multiplex all TCP sockets in a mobile device through a single socket to reduce TCP/IP overhead and thus conserve device and network resources.