An endoscopic treatment tool includes a sheath having a lumen, an elongated shaft inserted into the lumen and having an insertion passage, a stylet disposed in the insertion passage, an implant connected to the stylet, and a manipulation part main body provided on the sheath, a slider advanceable and retractable in an axial direction relative to the manipulation part main body, and a cam tube retracting while rotating in accordance with manipulation of the slider and having a spiral guide passage. A proximal end portion of the stylet has a projection engaged with the guide passage such that a force retracting the stylet is applied to the stylet by the cam tube retracting while rotating. The projection is slidable on the guide passage such that the stylet is advanceable relative to the elongated shaft against the force.