Invention Grant
- Patent Title: Methods of treating or preventing pruritis by blocking natriuretic polypeptide B
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Application No.: US15039982Application Date: 2014-12-04
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Publication No.: US09987330B2Publication Date: 2018-06-05
- Inventor: Mark A. Hoon , Santosh K. Mishra
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US DC Washington
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2014/068541 WO 20141204
- International Announcement: WO2015/085055 WO 20150611
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/10 ; A61K38/22 ; A01K67/027 ; C12Q1/68 ; A61K38/16 ; C12N15/85 ; A61K45/06 ; A61K38/17 ; C07K16/26 ; C12N15/113 ; A61K47/62
Abstract:
Disclosed is a method of treating, reducing, or preventing pruritis in a mammal, the method comprising administering at least one natriuretic polypeptide b (Nppb) blocking agent to a mammal in an amount effective to treat or prevent pruritis in the mammal. An in vitro method of identifying a compound that inhibits Nppb activity is also disclosed.
Public/Granted literature
- US20170014486A1 METHODS OF TREATING OR PREVENTING PRURITIS BY BLOCKING NATRIURETIC POLYPEPTIDE B Public/Granted day:2017-01-19
Information query
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