Invention Grant
- Patent Title: OMV vaccines
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Application No.: US14805119Application Date: 2015-07-21
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Publication No.: US09987345B2Publication Date: 2018-06-05
- Inventor: Renata Maria Grifantini , Oretta Finco , Erika Bartolini , Guido Grandi
- Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
- Applicant Address: BE
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE
- Agent Rebecca Stephens
- Priority: GB10098614 20100611
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A61K48/00 ; A01N65/00 ; A61K39/00 ; A61K39/385 ; A61K39/02 ; A61K39/108 ; A61K45/00 ; A61K39/118 ; C07K14/245 ; C07K14/295 ; C12P21/02 ; C12N1/20 ; C12N15/70 ; C12R1/19

Abstract:
The invention is in the field of outer membrane vesicles (OMV) and their uses. More particularly the present invention provides OMV obtained from a bacterium being an ompA mutant and/or a mutant in one or more components of the TolPal complex and presenting a heterologous antigen on its surface. The heterologous antigen is selected from the group consisting of Chlamydia trachomatis CT823, CT681, CT372, CT443, CT043, CT733, CT279, CT601 and CT153 for the treatment, prevention or diagnosis of Chlamydia infection.
Public/Granted literature
- US20160067327A1 OMV VACCINES Public/Granted day:2016-03-10
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