A plugged honeycomb structure includes: a plurality of honeycomb segments, a bonding layer, and plugging portions to plug open ends of cells of the honeycomb segment. Each honeycomb segment is configured so that the cells having at least two types of different shapes have a predetermined repeated sequence pattern. A circumferential-wall partially surrounded cell in which a partition wall and a segment circumferential wall are disposed so as to surround the cell has an area of open end that has a specific ratio to an area of open end of a partition-wall entirely surrounded cell including the cross-sectional shape of the circumferential-wall partially surrounded cell. The repeated sequence pattern of the cells is kept at a boundary between two of the honeycomb segments bonded with the bonding layer at an inflow end face and an outflow end face.