A thermoplastic elastomer tube can include a thermoplastic elastomer component disposed within a matrix. In an embodiment, the thermoplastic elastomer component is disposed within the matrix in a thermoplastic elastomer phase having a number of domains. At least approximately 50% of the domains of the thermoplastic elastomer component have an aspect ratio of no greater than approximately 1.5. In a particular embodiment, the thermoplastic elastomer tube comprises at least approximately 20 wt % of the thermoplastic elastomer component and no greater than approximately 50 wt % of a polyolefin component. In some embodiments, the thermoplastic elastomer component includes styrene.