Methods and apparatus for forming and installing insulation blankets in a vehicle compartment are disclosed. An example apparatus includes an insulation blanket that includes an outer layer, an insulation layer disposed in the outer layer, and a first fastener disposed in the insulation layer. The outer layer and the insulation layer are to form to a first channel. The first fastener is to receive, via the first channel, a first portion of a vehicle compartment frame to sealingly couple the insulation layer and the outer layer of the insulation blanket to the vehicle compartment frame.