Invention Grant
- Patent Title: Benzothiophene derivatives as estrogen receptor inhibitors
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Application No.: US14898782Application Date: 2014-07-01
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Publication No.: US09988376B2Publication Date: 2018-06-05
- Inventor: Sebastien Andre Campos , John David Harling , Afjal Hussain Miah , Ian Edward David Smith
- Applicant: GlaxoSmithKline Intellectual Property Development Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee Address: GB Brentford, Middlesex
- Agency: Locke Lord LLP
- Agent Bryan D. Zerhusen
- Priority: GB1311888.0 20130703
- International Application: PCT/EP2014/063899 WO 20140701
- International Announcement: WO2015/000867 WO 20150108
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D413/14 ; C07D409/12 ; C07D409/14 ; A61K31/422 ; A61K31/427 ; A61K31/435 ; A61K31/496 ; A61K38/05 ; A61K45/06 ; C07D471/10 ; C07K5/062

Abstract:
A compound of formula (I): or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, for example as inhibitors of the activity of the estrogen receptor, including degrading the estrogen receptor, the treatment of diseases and conditions mediated by the estrogen receptor.
Public/Granted literature
- US20160368911A1 BENZOTHIOPHENE DERIVATIVES AS ESTROGEN RECEPTOR INHIBITORS Public/Granted day:2016-12-22
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