Invention Grant
- Patent Title: 1 H-pyrazole and 4,5-disubstituted thiazole inhibitors of SYK
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Application No.: US14437307Application Date: 2013-10-23
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Publication No.: US09988378B2Publication Date: 2018-06-05
- Inventor: Niala Bhagirath , Joshua Kennedy-Smith , Matthew C. Lucas , Fernando Padilla
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: CH Basle
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: CH Basle
- International Application: PCT/EP2013/072132 WO 20131023
- International Announcement: WO2014/064134 WO 20140501
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D471/04 ; C07D401/04 ; C07D403/14 ; C07D409/04 ; C07D417/04 ; C07D417/14 ; A61K31/415 ; A61K31/4155 ; A61K31/427 ; A61K31/428 ; A61K31/437 ; A61K31/4439 ; A61K31/454 ; A61K45/06
Abstract:
The present invention relates to the use of novel compounds of formula (I), wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.
Public/Granted literature
- US20150266874A1 1 H-PYRAZOLE AND 4,5-DISUBSTITUTED THIAZOLE INHIBITORS OF SYK Public/Granted day:2015-09-24
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