Invention Grant
- Patent Title: ERK inhibitors
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Application No.: US15531771Application Date: 2015-12-10
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Publication No.: US09988397B2Publication Date: 2018-06-05
- Inventor: Phieng Siliphaivanh , David L. Sloman , David Witter , Umar Faruk Mansoor , Joseph Kozlowski , Ziping Liu , Jianmin Fu , Zhilong Wan , Wei Liu , Yimin Qian , Xianhai Huang
- Applicant: Merck Sharp & Dohme Corp. , MSD R&D (China) Co., Ltd.
- Applicant Address: US NJ Rahway CN Shanghai
- Assignee: MERCK SHARP & DOHME CORP.,MSD R&D (CHINA) CO., LTD
- Current Assignee: MERCK SHARP & DOHME CORP.,MSD R&D (CHINA) CO., LTD
- Current Assignee Address: US NJ Rahway CN Shanghai
- Agent Catherine D. Fitch; Richard S. Parr
- Priority: WOPCT/CN2014/093858 20141215
- International Application: PCT/US2015/064861 WO 20151210
- International Announcement: WO2016/100051 WO 20160623
- Main IPC: C07D498/18
- IPC: C07D498/18 ; C07D471/18 ; C07D471/22

Abstract:
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a method of inhibiting ERK2 in a patient in need of such treatment comprising administering to said patient an effective amount of at least one compound of Formula (I). The invention also provides a method for treating cancer in a patient in need of such treatment, said method comprising administering to said patient an effective amount of at least one compound of Formula (I).
Public/Granted literature
- US20170267695A1 ERK INHIBITORS Public/Granted day:2017-09-21
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