Invention Grant
- Patent Title: Thrombin-binding antibody molecules and uses thereof
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Application No.: US15348250Application Date: 2016-11-10
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Publication No.: US09988463B2Publication Date: 2018-06-05
- Inventor: James Andrew Huntington , Trevor Baglin , Jonathan Langdown
- Applicant: Janssen Pharmaceuticals, Inc.
- Applicant Address: US NJ Titusville
- Assignee: Janssen Pharmaceuticals, Inc.
- Current Assignee: Janssen Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Titusville
- Agency: Baker & Hostetler LLP
- Priority: GB1121513.4 20111214
- Main IPC: C07K16/40
- IPC: C07K16/40 ; C07K16/36
Abstract:
This invention relates to isolated antibodies which recognise the exosite 1 epitope of thrombin and selectively inhibit thrombin without promoting bleeding. These antibody molecules may be useful in the treatment and prevention of thrombosis, embolism and other conditions mediated by thrombin.
Public/Granted literature
- US20170066842A1 THROMBIN-BINDING ANTIBODY MOLECULES AND USES THEREOF Public/Granted day:2017-03-09
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