Invention Grant
- Patent Title: Non-natural nucleosides as theranostic agents
-
Application No.: US14342502Application Date: 2012-09-04
-
Publication No.: US09988680B2Publication Date: 2018-06-05
- Inventor: Anthony J. Berdis , Irene Lee , Edward Motea
- Applicant: Anthony J. Berdis , Irene Lee , Edward Motea
- Applicant Address: US OH Cleveland
- Assignee: Case Western Reserve University
- Current Assignee: Case Western Reserve University
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- International Application: PCT/US2012/053669 WO 20120904
- International Announcement: WO2013/033705 WO 20130307
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H19/04 ; C07H19/20 ; C07H19/044 ; G01N33/574
Abstract:
A composition for monitoring DNA damage includes a 3-ethynyl-5-nitroindolyl-2′-deoxyribose compound or pharmaceutically acceptable salt thereof and a detectable moiety with a click-reactive functional group that is complementary to the alkyne group of the compound.
Public/Granted literature
- US20140329236A1 NON-NATURAL NUCLEOSIDES AS THERANOSTIC AGENTS Public/Granted day:2014-11-06
Information query
