A ladder is provided which may include a positioning system, a fall arrest system, or both. In one embodiment, a rope and pulley system is provided wherein a first end of the rope is coupled to a base section of the ladder, a second end of the rope is coupled with a fly section of the ladder, and the rope extends between a plurality of pulleys. In one particular embodiment, the rope extends between five different pulleys, two being coupled with the fly section and three being coupled with the base section. At least one portion of the rope may extend along the side of the ladder (e.g., along the side of a rail of the fly section) while another section may extend up the front of the ladder between the rails and in front of the rungs. A fall arrest mechanism, or an ascender device, may be coupled with the section of rope extending up the ladder between the rails and in front of the rungs.