Disclosed is a system and method for facilitating optimizing cooling efficiency of a data center. The method may comprise receiving a layout of the data center. The method may comprise computing co-ordinates of each equipment of a plurality of equipments associated with the data center. Further, the method may comprise segregating the layout into a plurality of cells. The method may comprise capturing preliminary data associated with the data center. Further, the method may comprise determining a state value of the data center based upon the preliminary data. The method may comprise capturing CFD data and, selectively, thermal assessment data. Further, the method may comprise facilitating the optimization of the cooling efficiency of the data center by using an external analysis tool capable of performing Computational Fluid Dynamics (CFD) analysis or thermal assessment followed by the Computational Fluid Dynamics (CFD) analysis using the CFD data and the thermal assessment data.