Invention Grant
- Patent Title: Detecting and visualizing correlations between measured correlation values and correlation reference values of a pathway
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Application No.: US15178002Application Date: 2016-06-09
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Publication No.: US09990713B2Publication Date: 2018-06-05
- Inventor: Ralf Schoenmeyer , Sonja Althammer , Guenter Schmidt
- Applicant: Definiens AG
- Applicant Address: DE Munich
- Assignee: Definiens AG
- Current Assignee: Definiens AG
- Current Assignee Address: DE Munich
- Agency: Imperium Patent Works
- Agent Darien K. Wallace
- Main IPC: G06T7/00
- IPC: G06T7/00 ; G06F19/10 ; G06F19/00 ; G06K9/00

Abstract:
An analysis and visualization system analyzes a digital image of a tissue sample. In the sample, cells of a first type are stained in a first way, and cells of a second type are stained in a second way. The system segments the high-resolution image into first and second objects representing cells of the first and second types, respectively. The system also identifies a region of interest, and divides it into tiles. The system generates, for each tile, a first value and a second value. The first and second values for a tile are indicative of densities of the first and second objects in the tile. From the values, a measured correlation coefficient (CC) value is determined. The system compares the measured CC value to a reference CC value, thereby obtaining a correspondence value. The system then displays the image region along with a visualization of the correspondence value.
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